Thanks for contacting HCM You are concerned about a rash that is causing blisters and weeping sores on your hands. From your description I would say that you have something called pustular eczema. This is a real severe eczema but it can be controlled. In my practice I start with betamethasone ointment twice a day. Try to reduce the amount of hand washing as this makes the skin dry and react with the eczema. This will take several weeks to get control. I also recommend at night before going t sleep. put on the betamethasone and then put on a white cotton glove. The glove keeps the medicine in contact with the skin and also prevents the ointment rubbing onto your bed sheets. Hope this answers your question. Please contact us again with your medical concerns and questions