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Dr. Andrew Rynne

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What Could A Microsomal Antibodies Test Result ( 1.0) Indicate?

I am a 42 year old female, and I have 8/9 symptoms for Hashimoto disease (don t notice much hair loss). I was tested for microsomal antibodies and the test showed 1.0, is that a negative test? My TG Antibody test was 564.1 which was flagged high, and my T4, T3, and other tests are all in the normal range. I keep hearing that I probably have autoimmune issues, which is a very vague statement, and I am not sure what that means. I have a mass in my right thyroid that is around 2.6 centimeters, and has had 3 biopsies, all negative, and they found 2 more on my left thyroid one .64 cent., and one 1.6 cent.., I just went to an endo Dr. On Monday, he ordered the microsomal test which just came back. If you could let me know if any microsomal antibodies on the test is positive or negative since is is 1.0, and any suggestions for my next step would be greatly appreciated!
posted on Fri, 14 Mar 2014
Twitter Sun, 11 May 2014 Answered on
Twitter Mon, 12 May 2014 Last reviewed on
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Pathologist and Microbiologist,  's  Response
Hello and welcome to HCM,
Hashimoto's thyroiditis is an autoimmune disorder characterized by hyperthyroidism initially followed by hypothyroidism.
As you have mentioned that your TSH levels are raised and T3 and T4 levels are within normal range.
High TSH levels suggest presence of hypothyroidism.
The anti-microsomal antibodies should not be present in blood under nromal circumstances.
Thus, detection of anti-microsomal antibodies is a positive result.
Autoimmune disorders are ones in which the body starts producing autoantibodies against ones own body.
The treatment in Hashimoto;s thyroiditis is dual- to treat hypothyroidism and to combat the effect of autoantibodies.
The autoantibodies are blocked by steroids.

Thanks and take care
Dr Shailja P Wahal
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What Could A Microsomal Antibodies Test Result ( 1.0) Indicate?

Hello and welcome to HCM, Hashimoto s thyroiditis is an autoimmune disorder characterized by hyperthyroidism initially followed by hypothyroidism. As you have mentioned that your TSH levels are raised and T3 and T4 levels are within normal range. High TSH levels suggest presence of hypothyroidism. The anti-microsomal antibodies should not be present in blood under nromal circumstances. Thus, detection of anti-microsomal antibodies is a positive result. Autoimmune disorders are ones in which the body starts producing autoantibodies against ones own body. The treatment in Hashimoto;s thyroiditis is dual- to treat hypothyroidism and to combat the effect of autoantibodies. The autoantibodies are blocked by steroids. Thanks and take care Dr Shailja P Wahal