Hi, You need to get investigated for irregular periods. - Hypothyroidism itself causes irregular periods. You should get the thyroid problem solved with help of endocrinologist. The thyrodoxine tablet dose you are taking needs adjustment. Once you start taking optimum doses,thyroid won t cause any obstacle in conception. - Another common cause of irregular periods is PCOD. It is a condition arising due to hormonal imbalance& disturbs ovulation. A pelvic sonography & hormonal assay will be done to spot it. - Ovulation is a vital thing for conception. Please get ovulation study to be confirmed of it. - Husband s semen analysis should be checked for possible delay in conception. Any abnormality has to be treated specifically before trying for conception. All the investigations are to be carried out under a gynecologist s guidance. Thanks.