What Do These Blood Tests And Ultrasound Reports Signify?

Female patient 14 years old presented with ascites, odema of the lower limbs and hypertension plus pallor Ultrasound revealed organomegally (liver spleen and kidneys )liver biopsy revealed grsnulomatous liver disease ( epithyloid cells and macrophage but no eosinophil )PCR for tuberculosis in serum and ascetic fluid was negative ,serological tests were negative except for slightly reactive anti Smith and lupus anticoagulant .renal biopsy revealed picture of focal segmental glomerulosclerosis ..ESR was 150mm in the first hour ..he has also mild pleural effusion and pericardial effusion requiring aspiration ...Echo was done and there is systolic dysfunction ..CBC there is low haemoglobin 5.8 gram but wbcs and platelet are normal ..serum creatinine was 1.3 mg/dl reticulocytic count was 6% electrolytes were Norma he has short stature 139 cm and his weight is 39 kgm total serim bilirubin was 1.2 mg ....he recieved 4 bag of packed RBCs in the last 6 months he is highly intelligent but with delayed puberty ..what are the differential diagnosis .. At.is your DD?? Many thanks