Hi This activates the antioxidant systems, causing the release of cytokines and other immune stimulating factors that lead to healing in this therapy small and controlled amounts of ozone and oxygen are mixed and the mixture is administered into the body by different routes. it can be used to treat chronic bacterial and viral infections that don’t respond well to conventional antibiotics. It can also be used for the treatment of musculoskeletal like arthritis knee and disc prolapse. apart from this Ozone Therapy can be used for following 1.Conditions that don’t respond to conventional medicine. 2.Chronic infections. (like sinusitis in your case) 3.Painful ligaments and joints. 4.Stimulates the body’s own healing mechanisms. 5.pain management. hope this helps you take a call for ozone therapy its different from conventional therapy and you have to search for a good center feel free to ask us again our doctors will find a good one. good luck