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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Do You Suggest For ALT Measurement Being 61 After Liver Panel Test?

Hi , I got my liver panel test done today for taking Isonaizd, I see the ALT measurement is 61 which is slightly above the normal value. I m concerned about the same, appreciate if you could let me know the details. I m on Isonaizd since 2.5 months now Thanks, Shesh
posted on Sun, 16 Mar 2014
Twitter Thu, 28 May 2015 Answered on
Twitter Thu, 28 May 2015 Last reviewed on
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General & Family Physician,  's  Response
Hello,
I had gone through your question carefully and can understand your concern very well.

I would like to tell you that most of the time, ALT is very specific for liver disorders. As you are on Isoniazid for last 2.5 months and one of the severe side effects of this drug is hepatitis, but its very rare. Risk is increases as the age advances, so if you are more than 50 years of age, then chances of developing hepatitis is more as compared to younger ones.

Levels of ALT and AST are increased during 1st few months of starting treatment, but usually ALT levels return to normal after 3-4 months of treatment.

So in your case, as you have started isoniazid since 2.5 months and levels of ALT is not that much high, so at this point it doesn't seem to be an urgency and need any kind of evaluation, but i would recommend you to repeat the ALT and AST levels every monthly to rule out hepatitis. If the levels are consistently high after 4 months, then you need to consult a physician and need to be discussed about this.

Hope this answers your question and let me know if you have any further relevant queries, i will be happy to guide you further.
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What Do You Suggest For ALT Measurement Being 61 After Liver Panel Test?

Hello, I had gone through your question carefully and can understand your concern very well. I would like to tell you that most of the time, ALT is very specific for liver disorders. As you are on Isoniazid for last 2.5 months and one of the severe side effects of this drug is hepatitis, but its very rare. Risk is increases as the age advances, so if you are more than 50 years of age, then chances of developing hepatitis is more as compared to younger ones. Levels of ALT and AST are increased during 1st few months of starting treatment, but usually ALT levels return to normal after 3-4 months of treatment. So in your case, as you have started isoniazid since 2.5 months and levels of ALT is not that much high, so at this point it doesn t seem to be an urgency and need any kind of evaluation, but i would recommend you to repeat the ALT and AST levels every monthly to rule out hepatitis. If the levels are consistently high after 4 months, then you need to consult a physician and need to be discussed about this. Hope this answers your question and let me know if you have any further relevant queries, i will be happy to guide you further.