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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does A Reactive HBsAg Indicate?

Respected Sir I donated blood recently and cld find that HBsAg has shown reactive. I am 44 old guy. What does it actually mean. What I need to do now. Please advise. Is it something very serious Sir. Shall I need to take any precautions now... please advise. Thanks
Fri, 21 Oct 2016
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General & Family Physician 's  Response
Incomplete data like liver function tests and other serological tests for hepatitis B virus, etc...???
Test showing Reactive HBsAg is suggestive of acute or chronic hepatitis B virus infection.

The presence of HBsAg indicates that the blood and body fluids of the infected individual are highly contagious.

I advise you to consult your physician for further evaluation like certain lab tests including liver function tests, anti-HBS, HBeAg, IgM to HBcAg, etc.
to differentiate between acute or chronic infection.

You should also inform the blood bank officials about this result immediately.

There's no role of oral anti-HBV drugs at this stage.

However, you have to repeat the serological tests along with liver function tests after 6 months.

The absence of IgM anti-HBc or the persistence of HBsAg for 6 months along with the presence of HBeAg, reactive HBV DNA & Total Anti-HBc indicates chronic HBV infection.

In such a case you may be evaluated by specialist experienced in the management of chronic hepatitis B infection.

Currently, Pegylated Interferon alfa (PEG-IFN-a), Entecavir (ETV), & tenofovir are the first-line agents in the treatment of chronic hepatitis B disease.

Hope these answers your query.
Wishing you best of your health.
Take care
A feedback is appreciated.
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What Does A Reactive HBsAg Indicate?

Incomplete data like liver function tests and other serological tests for hepatitis B virus, etc...??? Test showing Reactive HBsAg is suggestive of acute or chronic hepatitis B virus infection. The presence of HBsAg indicates that the blood and body fluids of the infected individual are highly contagious. I advise you to consult your physician for further evaluation like certain lab tests including liver function tests, anti-HBS, HBeAg, IgM to HBcAg, etc. to differentiate between acute or chronic infection. You should also inform the blood bank officials about this result immediately. There s no role of oral anti-HBV drugs at this stage. However, you have to repeat the serological tests along with liver function tests after 6 months. The absence of IgM anti-HBc or the persistence of HBsAg for 6 months along with the presence of HBeAg, reactive HBV DNA & Total Anti-HBc indicates chronic HBV infection. In such a case you may be evaluated by specialist experienced in the management of chronic hepatitis B infection. Currently, Pegylated Interferon alfa (PEG-IFN-a), Entecavir (ETV), & tenofovir are the first-line agents in the treatment of chronic hepatitis B disease. Hope these answers your query. Wishing you best of your health. Take care A feedback is appreciated.