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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does High Liver Count Mean After Chemotherapy?

Hello, and thanks for being here.
my husband is receivinghis 4th chemotherapy as we speak. He has Hep C and his GGT is currently 755. (normal is 10-26)
He is getting carboplatin and alimenta combo and has stage 4 lung cancer. He is really doing quite well on the chemo, the tumors have shrunk a bit. Right now there are 2 tumors in one lung and malignant cells in the heart sac and in lymphnodes in both lungs. It has not traveled furthur so far as we know. Will they be able to give him more chemo with that high of liver counts? Is it normal to have such a hight GGT after 3 chemos?

I appreciate your answers. Thank you
posted on Thu, 13 Mar 2014
Twitter Sun, 21 Jun 2015 Answered on
Twitter Mon, 22 Jun 2015 Last reviewed on
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Radiologist,  's  Response
Hi,
Thanks for writing in.

The liver function tests including GGT might get elevated after chemotherapy. It is important to know his general condition and other levels like SGPT, SGOT, Alkaline phosphatase and bilirubin. If the tumor has shown response then chemotherapy might be continued after a gap. Since response to chemotherapy causes the tumor to break down and release toxins in to the blood stream therefore he might experience abnormal liver enzymes.

Any possibility of a secondary infection is to be ruled out and treated early. Often patients on chemotherapy might show increase in liver enzymes after 4 cycles and this guides the treatment. Please do not worry.
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What Does High Liver Count Mean After Chemotherapy?

Hi, Thanks for writing in. The liver function tests including GGT might get elevated after chemotherapy. It is important to know his general condition and other levels like SGPT, SGOT, Alkaline phosphatase and bilirubin. If the tumor has shown response then chemotherapy might be continued after a gap. Since response to chemotherapy causes the tumor to break down and release toxins in to the blood stream therefore he might experience abnormal liver enzymes. Any possibility of a secondary infection is to be ruled out and treated early. Often patients on chemotherapy might show increase in liver enzymes after 4 cycles and this guides the treatment. Please do not worry.