Hello
Thanks for writing to HCM
Mastoid air cell sclerosis  is due to 
chronic mastoiditis related to chronic suppurative otitis media(CSOM).She need proper examination of ear.Treatment depend upon findings.There may be many sequel of CSOM.
Chronic micovascular ischemia  in sub cortical 
white matter are related to ischemic changes resulting from involvement of small blood vessels.
Ischemic changes resulting from blood vessels changes in diseases like 
hypertension,
diabetes mellitus,dyslipidemia.
So,your mother need monitoring of conditions that leads to ischemic changes like hypertension,altered 
lipid profile,diabetes mellitus so that further progression of disease can be halted.
She need investigations like routine hemogram,RBS,LFT,RFT,Lipid profile,ultrasound of abdomen.
Proper treatment depend upon findings.
Hope i have answered your query.
Take Care
Dr.Indu Bhushan