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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does No Symptoms In Healthy Person In Case Of Tuberculosis Mean?

Good afternoon, I m a senior high school student at Marietta High School taking Anatomy and I am implementing a research on Tuberculosis. I have read many articles and sections from the cost of the treatments all the way to side effects, but one thing that has stumped me is as I read on and on about the topic I happened to cross paths with an intriguing article which stated, in a healthy person there are sometimes no symptoms . May you clarify to me what this means? And have researchers theorized any ways to improved the way to treat tuberculosis with the next 50 years or so? Thank you for your time. I am grateful to be able to communicate worth you. Have nice day Sincerely, Sade Leslie
posted on Thu, 1 May 2014
Twitter Mon, 1 Dec 2014 Answered on
Twitter Tue, 2 Dec 2014 Last reviewed on
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General & Family Physician,  's  Response
Hello Sade Leslie
It is very interesting that some one is curious to know about a typical thing that too about tuberculosis .
Now , the answer of your question:
TB spreads from person to person through the air by droplet nuclei containing Mycobacterium tuberculosis .
After inhalation , infectious droplet nuclei may reach respiratory bronchioles or alveoli.
Depending on bacterial virulence and the INHERENT HOST DEFENSE mechanisms of the alveolar macrophages, infection may be established and replication may ensue.
The tubercle bacillus grows slowly , dividing every 25 to 32 hours within macrophages.
Intially , there is no host resistance until a sufficient number of organisms are produced 2 12 weeks ( AND HOST REMAINS ASYMPTOMATIC , this is the answer of your question and this is a very helpful in the treatment for TB in next 50 years).
If within this duration the immunity or defense of host ( macrophages ) become able to kill Myco then host will not suffers with TB.
However , this is a short study but it is not possible here to write down in detail.
Hope this will be useful for you .
Good luck.
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What Does No Symptoms In Healthy Person In Case Of Tuberculosis Mean?

Hello Sade Leslie It is very interesting that some one is curious to know about a typical thing that too about tuberculosis . Now , the answer of your question: TB spreads from person to person through the air by droplet nuclei containing Mycobacterium tuberculosis . After inhalation , infectious droplet nuclei may reach respiratory bronchioles or alveoli. Depending on bacterial virulence and the INHERENT HOST DEFENSE mechanisms of the alveolar macrophages, infection may be established and replication may ensue. The tubercle bacillus grows slowly , dividing every 25 to 32 hours within macrophages. Intially , there is no host resistance until a sufficient number of organisms are produced 2 12 weeks ( AND HOST REMAINS ASYMPTOMATIC , this is the answer of your question and this is a very helpful in the treatment for TB in next 50 years). If within this duration the immunity or defense of host ( macrophages ) become able to kill Myco then host will not suffers with TB. However , this is a short study but it is not possible here to write down in detail. Hope this will be useful for you . Good luck.