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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does Phenytoin Level Of 34 Indicate?

Hellow Sir, I have taking Eptoin 100 (2 tablets) daily at bedtime since 1985. The last seizure was in 1996. My doctor tried to reduce the dose but due to relapse he advised me to continue-it was before 1996. I reside in Mumbai. Whenever I visit my home town I go for a review. Last review was in 2011. Recently my serum Phenytoin level was found to be 34 which is much above the normal range. Otherwise I am not finding any problem. Kindly advise what should be done in my case. Regards Pranab Saikia Mumbai contact:+91 0000
Wed, 2 Aug 2023
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Anesthesiologist 's  Response
Hello,

The total phenytoin reference range varies by age, as follows:
- Children and adults: 10-20 µg/mL
- Neonates: 8-15 µg/mL
- Toxic phenytoin levels are defined as greater than 30 µg/mL.

The following are few symptoms associated with toxic levels of phenytoin in serum:
1) Nystagmus or rapid movements of eyeballs
2) Slurring of speech
3) Ataxia or movement disorders
4) Tremors
5) Abnormal orofacial movements

As you do not have any of the above mentioned side effects, you don't need to worry. You can get the serum phenytoin checked once again after 6 months. As of now you don't need to worry and take the phenytoin tablet as usual as prescribed. Only if any of the above symptoms appear, then you need to consult your doctor for dose reduction.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Pallavi M., Anesthesiologist
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What Does Phenytoin Level Of 34 Indicate?

Hello, The total phenytoin reference range varies by age, as follows: - Children and adults: 10-20 µg/mL - Neonates: 8-15 µg/mL - Toxic phenytoin levels are defined as greater than 30 µg/mL. The following are few symptoms associated with toxic levels of phenytoin in serum: 1) Nystagmus or rapid movements of eyeballs 2) Slurring of speech 3) Ataxia or movement disorders 4) Tremors 5) Abnormal orofacial movements As you do not have any of the above mentioned side effects, you don t need to worry. You can get the serum phenytoin checked once again after 6 months. As of now you don t need to worry and take the phenytoin tablet as usual as prescribed. Only if any of the above symptoms appear, then you need to consult your doctor for dose reduction. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Pallavi M., Anesthesiologist