What Does Renal Concretions In Upper And Lower Pole Mean?

hi, my wife is having a problem from last few months, she is feeling too lethargic, even by doing a little work, she gets tired and feels short of breath, by doing medical test, doctors found out that there was blood and protein in the urine, ESR and C reactive protein was raised, there was a little blood pressure 150/80, X ray was clear, sonography tests revealed that there were multiple tiny renal concretions in upper and lower pole calyx and bilateral mildly raised renal cortical echotexture, by kidney function test there was creatinine level little raised, there is no pain anywhere in the body, no swelling in feet or hands, very low appetite