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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The Following Liver Biopsy Result Suggest?

July I had liver biopsy done. End of August final Dx are: A) Nodular Regenerative Hyperplasia with Portal Venopathy; B) Mild portal & central vein fibrosis; and C) Micro/Macrovesicular Steatosis involving 5% of Hepatocytes. Elevated GGT, AST & ALT were noted. Abdominal Ultrasound study essentially normal. Abdominal MRI with contrast essentially normal (some hemangiomas). I am 60.5 years old. Is this condition reversible? I was drinking socially, now stopped since March, 2016.
Mon, 22 Apr 2019
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General Surgeon,  's  Response
Hi,

SGOT and SGPT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests.

So the next step is to look for certain liver damage and the most common cause is fatty liver disease.

It should be confirmed by ultrasound. Other causes are viral hepatitis, cirrhosis, medications, alcohol intake or autoimmune diseases.

To verify the exact cause, US, bilirubin levels and tumor markers should be additionally done Then appropriate treatment can be started.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Ivan R. Rommstein, General Surgeon
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What Does The Following Liver Biopsy Result Suggest?

Hi, SGOT and SGPT are sensitive indicators of liver damage or injury from different types of diseases or conditions, and collectively they are termed liver tests or liver blood tests. So the next step is to look for certain liver damage and the most common cause is fatty liver disease. It should be confirmed by ultrasound. Other causes are viral hepatitis, cirrhosis, medications, alcohol intake or autoimmune diseases. To verify the exact cause, US, bilirubin levels and tumor markers should be additionally done Then appropriate treatment can be started. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Ivan R. Rommstein, General Surgeon