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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does The Liver Test Indicate?

On 3/2/15 my AST/SGOT was 28.0 U/L. On 8/25/15 my A1c was 6.0. On 3/10/16, my AST/SGOT was 120 u/l (not hemolyzed) and my ALT 111 u/l. My A1c on 3/10/16 was 6.7. Because of pain in my right leg (maybe due to back, hip, or knee problems), i was given a shot in L5 on 4/4/16 of Depo-Medrol. My Dr. is now treating me with metFORMIN 500 MG tablet for diabetes. X-rays show two fractures in the back which do cause pain, problems with hip and knee joints in both legs. My pain seems to come from my right hip to my right knee. I am using a back brace. My orthopedic doctor is trying to see if the pain is from my back (there is a vertabrae that is out of aligment). In the mean time, I am watching what I eat, losing weight from 232 to 119 lbs, and using metal crutches and a walker to get around. I have never been challenged like this before. My wight 20 years ago was 292 lbs. I have kept my weight off all these years. I am going for another pain shot on May 2,2016. I wonder if the pain injection caused my liver function to go up and my A1c to rise? Any thoughts?
Thu, 23 Jun 2016
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General & Family Physician,  's  Response
depot medrol is a steroid drug which has an effect of increasing blood glucose levels due to which your HbA1C is increased.It is metabolised in the liver to be effective on the body and hence there may be an elevation of liver enzymes is seen.regarding blood sugar control you need to focus on your diet,exercise and medication. You better discuss about the liver enzymes elevation with your ortho dr who can suggest tappering of this ,suggesting an alternative medicine and physiotherapy measures for your pain based on physical examination and some appropriate investigations.
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What Does The Liver Test Indicate?

depot medrol is a steroid drug which has an effect of increasing blood glucose levels due to which your HbA1C is increased.It is metabolised in the liver to be effective on the body and hence there may be an elevation of liver enzymes is seen.regarding blood sugar control you need to focus on your diet,exercise and medication. You better discuss about the liver enzymes elevation with your ortho dr who can suggest tappering of this ,suggesting an alternative medicine and physiotherapy measures for your pain based on physical examination and some appropriate investigations.