Hi, Thanks for writing in. Wegeners granulomatosis is a rare disorder involving the blood vessels. There is inflammation in the blood vessels and this causes restricted blood flow to the organs leading to disease conditions arising from deficient blood supply. Early treatment gives a good response but some patients might need treatment for 18 to 24 months. Treatment is with chemotherapeutic drugs, corticosteroids, immune suppressants and biologic therapy. In your case, the kidney needs to be protected from further damage and saved. With a creatine of 2.2 there is a chance of disease stabilization and response to treatment. The first year after diagnosis is important. If a patient can make it through a year on treatment then 90% of patients improve with aggressive medical treatment and 75% of patients achieve remission. However, the relapse rate is 50% and this happens after 7 to 8 years. This can also be treated when it happens. The outlook to survival is good after one year of treatment.