What Is The Cause And Treatment For Sudden Drop In Blood Values, Night Sweats And Persistent Leg Edema In One On Hemodialysis ?

My mother has been on hemodialysis for the last 2 years. The consistent feature was that her hemoglobin levels never went past 7 mg dl for 2 years despite erythropoietin injections. She has had anaphylactic reactions to oasis, penicillin and aspirin in 2011; she has had chronic leg and foot edema Since her aspirin allergy. In feb 2012 , she had chills and fever and sudden abdominal pain and distension- initially thought as peritonitis, but diagnosed later as rectus sheath hematoma; last 3 weeks she developed sudden pancytopenia with platelets dropping to 0000; she was transfused 2 whole units of blood; some reversal of hematocrit has happened; heparin has been stopped; she has seen a hematologist and had a bone marrow biopsy done ; currently awaiting test results; for the last one week, she has had alternating fever, chills and weakness ( currently awaiting blood culture results to see if there s post biopsy infection) and also excessive++ night sweats ,mostly after dialysis. I am wondering about the likely causes of her sudden drop in blood values, the reason for the persistent leg edema ( not classical pitting edema; has not changed much with dialysis; nephrologist not sure if allergic or chronic) and the reason for the night sweats Any recommendations tests or Rx wise Thank you kindly