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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Is The Cause For Bilateral Polycystic Ovaries?

hi good morning doc, i have PCOS and my doctor told me that i am diabetic which is genetic, this made me think if how i got diabetic since my parents don't have diabetes?. what are the causes of bilateral polycystic ovaries? is it curable?..and how does pcos related to diabetes? doc. i am not fat or obese, my weight is 46 and i am 21 yrs. old.. i am hoping for your response, thank you.
Wed, 26 Feb 2014
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OBGYN 's  Response
Hi and welcome to healthcare magic.

I completely understand your concern. You have a lot of queries and I will answer them one by one:

1. How is it that you have diabetes: The reason your doctor said that your sugar is more likely to be genetic is because you are having it at a younger age. Diabetes most likely occurs after the age of 40 and those who have genes that make them prone for diabetes get it at an early age. The genes causing this are recessive meaning if there is one normal gene and one abnormal gene than the abnormal gene is suppressed and diabetes does not develop. But since the person carries this gene, he or she can pass it off to her children [either the normal one or the abnormal one]. If both parents carry one abnormal gene and one normal gene and the child inherits only the abnormal genes from each parent, the child gets diabetes as there is no normal gene to suppress the abnormal ones. Another possibility is that the child did have a normal gene but during the process of growth, the normal gene was damaged [mutation] and only the abnormal one is now acting to produce diabetes. So it is not that every diabetes will have affected parents and also not all affected parents will have children with diabetes. Also diabetes is linked to multiple genes so it is difficult to say who will be affected.

2. Polycystic ovaries: they are caused by trapping of the maturing female eggs or ova inside the ovary. This happens as the hormonal conditions are not favorable within the ovary as well as within the body to allow ovulation and release of ova. The trapped ova again lead to hormonal imbalances and set up a vicious cycle. Diabetes leads to abnormalities in insulin which is an important hormone influencing the levels of other hormones. All of this causes hormonal imbalance leading to PCOS.
There is a type of PCO called lean PCO where body fat does not influence the development of PCO.

3. Is PCO curable: Well it depends on how we define cure. The problem of ovulation may lead to infertility which can be dealt with by usingdrugs to produce ovulation or drilling the ovary by laparoscopy. Problems of irregular periods can be corrected by using birth control pills that also deal with acne and excess hair growth which are common issues with PCO.
Many a times after drilling and pregnancy, women do not have symptoms of PCO due to the correction in local hormonal imbalances by drilling and pregnancy.

So as of now, concentrate on correcting your sugars. There are so many people living with diabetes. Do not worry. Once the sugars are controlled, look how symptoms of PCO behave and direct further treatment accordingly after consulting your gynecologist and endocrinologist.

Hope this answered your query.

Feel free to ask any more and I would be gald to help.
Dr Madhuri Bagde
Consultant Ob GY
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What Is The Cause For Bilateral Polycystic Ovaries?

Hi and welcome to healthcare magic. I completely understand your concern. You have a lot of queries and I will answer them one by one: 1. How is it that you have diabetes: The reason your doctor said that your sugar is more likely to be genetic is because you are having it at a younger age. Diabetes most likely occurs after the age of 40 and those who have genes that make them prone for diabetes get it at an early age. The genes causing this are recessive meaning if there is one normal gene and one abnormal gene than the abnormal gene is suppressed and diabetes does not develop. But since the person carries this gene, he or she can pass it off to her children [either the normal one or the abnormal one]. If both parents carry one abnormal gene and one normal gene and the child inherits only the abnormal genes from each parent, the child gets diabetes as there is no normal gene to suppress the abnormal ones. Another possibility is that the child did have a normal gene but during the process of growth, the normal gene was damaged [mutation] and only the abnormal one is now acting to produce diabetes. So it is not that every diabetes will have affected parents and also not all affected parents will have children with diabetes. Also diabetes is linked to multiple genes so it is difficult to say who will be affected. 2. Polycystic ovaries: they are caused by trapping of the maturing female eggs or ova inside the ovary. This happens as the hormonal conditions are not favorable within the ovary as well as within the body to allow ovulation and release of ova. The trapped ova again lead to hormonal imbalances and set up a vicious cycle. Diabetes leads to abnormalities in insulin which is an important hormone influencing the levels of other hormones. All of this causes hormonal imbalance leading to PCOS. There is a type of PCO called lean PCO where body fat does not influence the development of PCO. 3. Is PCO curable: Well it depends on how we define cure. The problem of ovulation may lead to infertility which can be dealt with by usingdrugs to produce ovulation or drilling the ovary by laparoscopy. Problems of irregular periods can be corrected by using birth control pills that also deal with acne and excess hair growth which are common issues with PCO. Many a times after drilling and pregnancy, women do not have symptoms of PCO due to the correction in local hormonal imbalances by drilling and pregnancy. So as of now, concentrate on correcting your sugars. There are so many people living with diabetes. Do not worry. Once the sugars are controlled, look how symptoms of PCO behave and direct further treatment accordingly after consulting your gynecologist and endocrinologist. Hope this answered your query. Feel free to ask any more and I would be gald to help. Dr Madhuri Bagde Consultant Ob GY