Hi, Thanks for writing in. The condition Thrombotic microangiopathy (TMA) is a well-documented but severe complication that occurs after kidney transplant. Treatment of posttransplantation TMA relies on removal of any precipitating factors, relief of symptoms, and PE or plasma infusion. Therapeutic options for posttransplant TMA, including plasma therapy and targeted complement inhibitors can be used to treat those suffering from TMA. With latest guidelines, there have been patients with TMA who were completely treated at the end of one year with hospitalization and maintenance immune suppression. The response to treatment varies in every patient and we pray that your friend makes a complete recovery at the earliest.