How long does it take non hodgkins lymphoma to reach stage 3 I have what is called diffuse large B cell type Lymphoma the aggressive type. I also have been diagnosed with severe Cornary Artery Disease, need a by-pass but because of the cancer no doctor will touch me. and I am worried about the upcoming Chemo treatments I will be haveing CHOP, can you tell me if there is a possibility of more heart damage during chemo I am 54 yrs old 5'2 159 lbs history of type two diabetes, high chlosterol, hypertention, asthma.