Hello Dr. Taraknath My father is your patient. He recently visited you. He had previous TIA. He has been on clopidogrel and aspirin combination for the past 5 years. according to match trial iam giving the reference below this combination does not offer any benefit for secondary prevention of stroke and is associated with increased risk of bleeding. Can you please take a second look at his medication. Thank youLancet. 2004 Jul 24-30;364(9431):331-7. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, Leys D, Matias-Guiu J, Rupprecht HJ; MATCH investigators. SourceDepartment of Neurology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany. YYYY@YYYY