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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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When Will Creatinine Level Normalize After PCNL For Renal Stones?

Hi

my mother had operation PCNL on both kidney on 25.10.11. she had stone on right kidney with moderate palvicalyceal dilatation and stone on left kidney also with normal pc system.but her s.creatinine was 1.5. she had PCNL on both kidney with DJ stent on right which was removed on 8th POD.

on 15.11.11 she has done a s. creatinine level which is 1.4.(normal value 1.2).

she in 58 years ,Hypertensive (on Cavapro) and DM( Amaryl 2 mg) .she also had low dose ecosprin and vastaral mr as her ecg shows septal ischaemia.(echo: normal).



is the creatinine level is worried . how long it take to normalize the creatinine level after relief of obstruction.what precaution she need to have
Fri, 24 Oct 2014
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Radiologist 's  Response
Hi,
Thanks for writing in.

I suspect there was a large stone causing obstruction and hydroureteronephrosis in the right kidney. Subsequent percutaneous nephrolithostomy (PCNL) treatment was done to treat the stone. The serum creatinine level goes up due to urinary obstruction, probably the right kidney stone in your mother. Since the obstruction was present for some time in the past, the kidney function might have got affected. As per medical literature, a kidney stone causing obstruction for more than 10 days can cause obstructive uropathy which is form of permanent damage leading to the kidney being unable to function properly. The raised creatinine is a consequence of this obstruction and a level of 1.4 is borderline high. It is most likely that the kidney was not much affected by the duration of obstruction by the stone. Serum creatinine is to be repeated after 2 - 3 months and it will most likely come down to normal. Since she is having diabetes and hypertension, regular kidney function tests should be done every 6 months. Creatinine can also rise due to hypertension and diabetes.
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When Will Creatinine Level Normalize After PCNL For Renal Stones?

Hi, Thanks for writing in. I suspect there was a large stone causing obstruction and hydroureteronephrosis in the right kidney. Subsequent percutaneous nephrolithostomy (PCNL) treatment was done to treat the stone. The serum creatinine level goes up due to urinary obstruction, probably the right kidney stone in your mother. Since the obstruction was present for some time in the past, the kidney function might have got affected. As per medical literature, a kidney stone causing obstruction for more than 10 days can cause obstructive uropathy which is form of permanent damage leading to the kidney being unable to function properly. The raised creatinine is a consequence of this obstruction and a level of 1.4 is borderline high. It is most likely that the kidney was not much affected by the duration of obstruction by the stone. Serum creatinine is to be repeated after 2 - 3 months and it will most likely come down to normal. Since she is having diabetes and hypertension, regular kidney function tests should be done every 6 months. Creatinine can also rise due to hypertension and diabetes.