Generally antibiotics are used more commonly by elderly than younger patients because of their more susceptibility of infection due to depressed immunity. Physiologic changes associated with aging result in altered pharmacokinetics and accurate estimates of renal function cannot be made with standard methods. Because of a higher prevalence of other chronic diseases, there is a greater possibility for
polypharmacy and a resulting risk of an adverse event &
drug interaction. Altered physiology leads to altered pharmacokinetics, so the most appropriate dose in an elderly person may not be the dose that is used in the general population. So it is very difficult to specify particular antibiotics which are completely safe for elderly. It depends upon the clinician, your comorbidities and concomitant medications. But in general,
1. lowest effective dose is considered safe in elderly
2. use of more than one antibiotic at a time is avoided
3. treatment duration is kept minimum
4. polypharmacy is avoided as far as possible
5. use only when you need and avoid indiscriminate use
6. preferably select antibiotic after culture and sensitivity report
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