Hello Thanks for query .You have been smoking and consuming alcohol occasionally and want to donate kidney . The ill effects of smoking or alcohol are short lasting and does not disqualify an individual from donating kidney . Following basic tests are done prior to qualify donor to be for donating kidney before one decides to donate kidney . 1) The blood group of the donor should be same as that of recipient (Person to whom kidney is being transplanted ) 2) HLA typing this is highly specific test to decide whether donated kidney will be accepted in recipients body or not and what will be the chance of rejection . 3) Renal function test of a donor to assess the status of the donors kidney whether it is normal or damaged due to preexisting disease 4) Renal angiography to asses the vascular anatomy of the renal vessels to know technical feasibility for vascular anastomis during transplant surgery 5) Not but the least status of cardiac , lever and pulmonary functions to assess fitness for anesthesia to undergo major surgery . Dr.Patil..