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Are There Any Negative Interactions Between Paracetamol, Avil And Ibuprofen?

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Posted on Wed, 5 Aug 2015
Question: can a combination of paracetamol 650mg, avil 50 mg, ibuprofen 400 mg and alprazolam 0.5 mg be fatal or deadly when consumed in overdose????????

what is the fatal overdose of all the above said medicines????? what will be the outcome if one consumes those???????
doctor
Answered by Dr. Shubham Mehta (2 hours later)
Brief Answer:
combination is not fatal.

Detailed Answer:
Hello
Welcome to HCM.
I understand your concerns.

Paracetamol, avil, alprazolam and ibuprofen does not have significant clinical interactions. The combination is not fatal in above dose.
These doses can causes sedation, gastritis and vomiting.

The fatal dose of paracetamol is 150mg/kg, and of ibuprofen is 400mg/kg.

Fatal dose of alprazolam and avil has not been established. But alprazolam as high as 20mg in a day and avil 500mg in a day have been tolerated by patients.

Hope this addresses your concerns satisfactorily.

Feel free to ask further.
Take care.
Thanks.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Shanthi.E
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Answered by
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Dr. Shubham Mehta

Psychiatrist

Practicing since :2008

Answered : 2145 Questions

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Are There Any Negative Interactions Between Paracetamol, Avil And Ibuprofen?

Brief Answer: combination is not fatal. Detailed Answer: Hello Welcome to HCM. I understand your concerns. Paracetamol, avil, alprazolam and ibuprofen does not have significant clinical interactions. The combination is not fatal in above dose. These doses can causes sedation, gastritis and vomiting. The fatal dose of paracetamol is 150mg/kg, and of ibuprofen is 400mg/kg. Fatal dose of alprazolam and avil has not been established. But alprazolam as high as 20mg in a day and avil 500mg in a day have been tolerated by patients. Hope this addresses your concerns satisfactorily. Feel free to ask further. Take care. Thanks.