Brief Answer:
They are very rare possibilities

Detailed Answer:
Hello XXXXXXX

Thanks for posting on XXXXXXX

Barrett's esophagus is a condition in which the cells of your lower esophagus become damaged, usually from repeated exposure to stomach acid. The damage causes changes to the color and composition of the esophagus cells. It is more of a complication of Gastroesophageal reflux diseases(GERD). Looking at the pathophysiology of the diseases, it will be had to relate lack of digestive enzymes and barrett's diseases, since it will not affect structures or organs that produce the enzymes. So, NO, I doubt if the diseases can cause lack of digestive enzymes. But in the other hand, since the diseases can cause nutritional disorder or malnutrition, it is possible to have iron deficiency (which is an extremely rare possibility). Iron deficiency anemia can also come as a result of digestive bleeding (which is another possible complication of barrett's esophagus).
You will need an esophagogastroduodenoscopy (EGD) in order to determine the extend to which the diseases has progressed and also occult blood test (in stool).

I will suggest you worry less about those two complications as they are less likely to occur.

Hope this helps and wish you the best
Dr. Nsah

---

Brief Answer:
Both conditions may be related to a liver diseases

Detailed Answer:
Hello,

Thanks for the update,

Well both conditions might be related to a liver diseases and b12 deficiency could manifest with easy bruising symptoms such as the blisters you might be describing. Pernicious anemia, a condition in which there is a lack of a protein called intrinsic factor. The protein, which is made in the stomach, is necessary for vitamin B12 absorption.
- Atrophic gastritis, a thinning of the stomach lining that affects up to 30% of people aged 50 and older.
- Conditions affecting the small intestine, such as Crohn's disease, celiac disease, bacterial growth, or a parasite.
- Excessive alcohol consumption.
- Autoimmune disorders, such as Graves' disease or systemic lupus erythematosus
- Long-term use of acid-reducing drugs.
This means that, your doctor would need to do an extensive work-ups in order to determine the possible causes of your Vitamin B12 deficiency (even though yours seem obviously to be hereditary and may likely be an autoimmune condition). If any underlying problem can be detected then treatment for the condition can be provided along side supplementation with Vitamin B12.
Your barrett's esophagus may likely also be the cause of this vitamin B12 deficiency given that there is most likely going to be a malnutrition condition.
You should slow down with use of anti-acids (if you were already using).
I suggest you also book an appointment to see a gastroenterologist.

Hope this helps and wish you the best.
Dr. Nsah

---