Diabetic, Taking Novolog & Glargine. Chances Of Having Resistance?

Posted on Sun, 21 Jul 2013

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sun, 21 Jul 2013 Answered on

Thu, 22 Aug 2013 Last reviewed on

Question : Am adult onset Type I Diabetic. Well controlled on Novolog & Glargine. Recently Glargine does not seem to be working as it has in the past. Is it possible to develop resistance to Lantus or is there a history of loss of effectiveness over time?

Answered by Dr. Nsah Bernard (2 hours later)

Hello,

Thanks for posting,

Resistance to injection insulin (lantus/insulin glardin) is extremely rare. You will first of all need to consider dosage first before thinking of resistance. Maybe if your doctor increase the dosage of glardine, then your diabetes might be able to be controlled. Also, it is possible too that with increasing age, you might have developed Type II Diabetes which will require other forms of treatment rather than the one you have been on through out your life.
It will be best to discuss this with your treating physician and he can then establish a much more recent recommendation for you.

Hope this helps and wish you the best.
Dr. Nsah

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar