Does Adderall Have An Effect On Ejection Fraction?

Posted on Tue, 7 Mar 2017

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Tue, 7 Mar 2017 Answered on

Wed, 3 May 2017 Last reviewed on

Question : What effect if any does adderal have on ejection fraction?

Answered by Dr. Rishu Saxena (1 hour later)

Brief Answer:
Amphetamines causes cardiomyopathy and decreases ejection fraction.

Detailed Answer:
Hi,
Thanks for asking the query,

As per your question Amphetamine and its derivatives in long term decreases the ejection fraction of heart usually because of enlargement of heart muscles called cardiomyopathy.

Ejection fraction can be increased by using 3 classes of drugs-

1) Trimetazidine- doses of around 35mg given twice daily causes elevation of ejection fraction.

2) ACE inhibitor abd AT1 antagonists- Prevent cardiac remodelling and improves EF in long term usually used are Ramipril, Losartan etc.

3) Potassium sparing diuretic like Eplerenone .

Though used in developing countries Trimetazidine is not approved by FDA.
Please discuss these options with your cardiologist.

Regards..

Above answer was peer-reviewed by : Dr. Yogesh D