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Does Lamictal Interact With Valproic Acid?

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Posted on Mon, 8 May 2017
Twitter Mon, 8 May 2017 Answered on
Twitter Tue, 30 May 2017 Last reviewed on
Question : my wife is currently taking valproic acid and the nursing home psychiatriast wants to start her on 25mg lamictal. from what I read that combination could cause serious side effects.
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Answered by Dr. salah saad shoman (30 minutes later)
Brief Answer:
Major interaction

Detailed Answer:
There is a major drug interaction between these two medications. which means the interaction is clinically significant and should be avoided as the risk of interaction overweighs the benefit.. This combination may cause skin rash, restlessness, seizures, tremors, muscle weakness, and staggering walk. I hope I answered your question.
Above answer was peer-reviewed by : Dr. Raju A.T
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Dr. salah saad shoman

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Practicing since :2004

Answered : 3147 Questions

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Does Lamictal Interact With Valproic Acid?

Brief Answer: Major interaction Detailed Answer: There is a major drug interaction between these two medications. which means the interaction is clinically significant and should be avoided as the risk of interaction overweighs the benefit.. This combination may cause skin rash, restlessness, seizures, tremors, muscle weakness, and staggering walk. I hope I answered your question.