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Does S-Adenosylmethionine Interact With Tacrolimus, Mycophenolate Mofetil, Levothyroxine And Atorvastatin?
Posted on
Wed, 1 Feb 2017
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Wed, 1 Feb 2017
Answered on
Mon, 27 Feb 2017
Last reviewed on
Question : Hi I have had a renal transplant 3 years ago and would like to take s-adenosylmethione I am on other medication. I would like to have a consultation with a nephrologist or kidney specialist. I take actrapid(insulin)tds, alendronic acid 70mg once a week, adcal d3 bd , mycophenolate 500mg bd, Tacrolimus, levothyroxine 25mcg, atorvastatin 10mg, dustatsteride 500mg of, bethanechol 25mg,fenofibrate160mg 10d, diltiazem 120mg 10d, , pantoprazole 20mg 1od, Prednisone 10mg 1od.
Brief Answer:
you can take it
Detailed Answer:
hi,
Taking XXXXXXX at the same time as tacrolimus and mycophenolate has not shown any interaction. drugs like Dextromethorphan, Meperidine, Pentazocine, Tramadol may increase the risk of serotonin syndrome (a potentially dangerous condition caused by having too much serotonin in your body). So i think it is safe for you to take it
but it will be a good idea to check tacrolimus levels 15 days after starting the dose.
Out of medications listed here, we do know that diltiazem increases tacrolimus blood levels and i am sure your doctor must be monitoring that.
also i want to emphasize that combination of fenofibrate with atorvatastin in patients who have higher than normal creatinine level can lead to increase in serum creatinine levels. so should be monitored for same.
best wishes
you can take it
Detailed Answer:
hi,
Taking XXXXXXX at the same time as tacrolimus and mycophenolate has not shown any interaction. drugs like Dextromethorphan, Meperidine, Pentazocine, Tramadol may increase the risk of serotonin syndrome (a potentially dangerous condition caused by having too much serotonin in your body). So i think it is safe for you to take it
but it will be a good idea to check tacrolimus levels 15 days after starting the dose.
Out of medications listed here, we do know that diltiazem increases tacrolimus blood levels and i am sure your doctor must be monitoring that.
also i want to emphasize that combination of fenofibrate with atorvatastin in patients who have higher than normal creatinine level can lead to increase in serum creatinine levels. so should be monitored for same.
best wishes
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
hi is there any clinical trials where this supplement has been used in renal transplants
Brief Answer:
No interaction
Detailed Answer:
Hi,
I did a recent search on pubmed . No reports to suggest any interaction.
In any case it is only just amino acid compound and not likely to interact with immunosuppression medicines.
Best wishes
No interaction
Detailed Answer:
Hi,
I did a recent search on pubmed . No reports to suggest any interaction.
In any case it is only just amino acid compound and not likely to interact with immunosuppression medicines.
Best wishes
Above answer was peer-reviewed by :
Dr. Arnab Banerjee
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