Question: i have had seen, by R.M, choroidal plexus cysts on the atria of the ventricles with diffusion more serrated at left.Areas of possible gliosis of vascular or traumatic origin were also seen .These cysts were not seen on the past years considering I monitor brain for a lesion on dx unco.para-hippocampical region, that is retained to have been caused by mutation od adenomatous polyposis coli gene. I have mutation 3926 of the 5' of the gene with deletions of 5 bp, considered germinal and truncant mutation who cause premature stop codon (IST Genua). Other lesion on the same area, but more superficial, was seen on 2006 and attribuited to infartual esit. For APC/Wnt pathway are part on organogenesis of choroidal plexus, other then controll and govern APC
retinoic acid synthesis and for his mutation cause
hyperaldosteronism, i have, my question is: may these cysts progress, the gliosis, who is fibrosis, causes
sclerosis and interest hearts, lungs and organs related, being APC present on glial neurons and govern the polarisation of radial glia, and being present on purkinje neurons, by whom origin ondusction system of heart? May these cysts cause a
intracranial hypertension, also caused by hyperaldosteronism, how, other than normal periodic controlls by imaging, know the real situation that, being of genetic origin, may involve? These question for i have already been interessed by toal
colectomy, ilostony, total
gastrectomy with asportation of 1/3 of duodenal bulb, left surrenalectomy, other intervents of
ileostomy for adenoK, subocclusion, porlpse, subocclusion. Kind regards XXXX