How Long Does Propranolol Remain In The System?

Posted on Mon, 10 Nov 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Mon, 10 Nov 2014 Answered on

Wed, 3 Dec 2014 Last reviewed on

Question : Took 20mg of propranolol lowered my heart rate but now blood pressure is 89/49. How long will this be in my system.

Answered by Dr. Vivek Chail (1 hour later)

Brief Answer:
In 48 hours the drug is out of your system.

Detailed Answer:
Hi XXXX,
Thanks for writing in to us.

I have read through your query in detail.
Propranolol is a nonselective beta-adrenergic receptor blocking agent possessing no other autonomic nervous system activity that has been evaluated for management of patients with the manifestations of cardiovascular disorders. At your age the drug is eliminated with a mean terminal half-life of approximately 6 hours.

20 mg is a small dose and not a concern. 24-48 hours is more than sufficient for the effects of the drug to dissipate. In 2 days or 48 hours, most of the medication is out of the system.

Hope this answers your question. Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek

Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar