HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

How Long Does The Liver Take To Heal After Drug Induced Hepatitis?

default
Posted on Tue, 5 Nov 2013
Question: How long does the liver take to heal after drug induced(Macrobid) hepatitis?
YYYY@YYYY
doctor
Answered by Dr. Pavan Kumar Gupta (1 hour later)
Brief answer...it is variable from few weeks to many months and sometimes can cause liver failure.
Detailed answer..
Hello,
Thanks for the query.
MACROBID ( Nitrofurantoin )  is an oral antibiotic and one  of the most common causes of drug induced liver disease and can cause either an acute or a chronic hepatitis-like syndrome that can be severe and lead to liver failure or cirrhosis.
The acute liver injury usually subsides rapidly in few weeks once the drug is withdrawn but sometimes it can cause acute liver failure.
The chronic form of liver toxicity is much more common than acute liver toxicity and typically occurs after a prolonged longterm therapy.
Severity of nitrofurantoin induced injury ranges from just simple elevation of liver enzymes to fulminant liver failure failure and death.
Generally complete recovery takes place after stopping the drug but the recovery may be slow in some cases and may take 3 to 6 months.
In rare cases the evidence of chronic liver injury persists.
I hope it helps however you may revert to me for any further query.
Best of luck
Thanks
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Pavan Kumar Gupta

General & Family Physician

Practicing since :1978

Answered : 6704 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
How Long Does The Liver Take To Heal After Drug Induced Hepatitis?

Brief answer...it is variable from few weeks to many months and sometimes can cause liver failure.
Detailed answer..
Hello,
Thanks for the query.
MACROBID ( Nitrofurantoin )  is an oral antibiotic and one  of the most common causes of drug induced liver disease and can cause either an acute or a chronic hepatitis-like syndrome that can be severe and lead to liver failure or cirrhosis.
The acute liver injury usually subsides rapidly in few weeks once the drug is withdrawn but sometimes it can cause acute liver failure.
The chronic form of liver toxicity is much more common than acute liver toxicity and typically occurs after a prolonged longterm therapy.
Severity of nitrofurantoin induced injury ranges from just simple elevation of liver enzymes to fulminant liver failure failure and death.
Generally complete recovery takes place after stopping the drug but the recovery may be slow in some cases and may take 3 to 6 months.
In rare cases the evidence of chronic liver injury persists.
I hope it helps however you may revert to me for any further query.
Best of luck
Thanks