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Is Topiramate Effective In Weight Loss Treatment While On Amisulpride And Escitalopram?

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Posted on Mon, 12 Dec 2016
Question: Hi, Iam using Amisulpride 50mg and Escitalopram 10mg since 2 years for my health anxiety and found to have significant improvement. But I have seen weight gain after having these tablets. A doctor told me to continue Amisulpride 50mg and Escitalopram 10mg for 2 more months and additionally have Topiramate 25mg for 2 months for weight loss. My question is how safe is Topiramate 25mg for 2 months usage ? Will it effect the brain and cause drowsiness all through the day ? Is Topiramate 25mg really effective for weight loss ? Will Topiramate increase the risk of Glaucoma (since my father has Glaucoma) ?
doctor
Answered by Dr. Seikhoo Bishnoi (48 minutes later)
Brief Answer:
Topiramate is safe to use.

Detailed Answer:
Hi thanks for the query

I can understand your concern. Both Escitalopram and Amisulpiride are known to cause weight gain after regular use. Topiramate is a mood stabiliser that is very beneficial in weight loss.

- Topiramate is safe to use for weight loss.
- The drug doesn't cause drowsiness or sedation in day time. No need to worry.
- The drug if used regularly helps in weight loss especially in doses 100 or more per day. Dose of 25 mg will not have much effects but the drug will help in weight loss.
- The drug can be used in glaucoma patients but with caution. The drug might precipitate closed angle glaucoma. So should be avoided only if doctor agrees.

Thanks and Take care.

hope this helps you please don't hesitate to ask again for more information.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Seikhoo Bishnoi (20 hours later)
Thanks for the prompt response. I would also like to know if Topiramate has withdrawal symptoms after using it for 2 months and then stop ? Does it cause any damage of the central nervous system on prolonged usage?
doctor
Answered by Dr. Seikhoo Bishnoi (13 minutes later)
Brief Answer:
Topiramate is safe to use.

Detailed Answer:
Hi thanks for asking a follow up

Topiramate if stopped after regular use can cause withdrawal symptoms so should not be stopped abruptly. Better to reduce the doses gradually over 4 weeks and this dose reduction would not cause withdrawal symptoms.

The drug doesn't cause CNS damage on prolonged use. In some individuals cognitive decline was reported in some studies. But in my clinic I haven't reported any such side effect.

Thanks. Take care
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

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Is Topiramate Effective In Weight Loss Treatment While On Amisulpride And Escitalopram?

Brief Answer: Topiramate is safe to use. Detailed Answer: Hi thanks for the query I can understand your concern. Both Escitalopram and Amisulpiride are known to cause weight gain after regular use. Topiramate is a mood stabiliser that is very beneficial in weight loss. - Topiramate is safe to use for weight loss. - The drug doesn't cause drowsiness or sedation in day time. No need to worry. - The drug if used regularly helps in weight loss especially in doses 100 or more per day. Dose of 25 mg will not have much effects but the drug will help in weight loss. - The drug can be used in glaucoma patients but with caution. The drug might precipitate closed angle glaucoma. So should be avoided only if doctor agrees. Thanks and Take care. hope this helps you please don't hesitate to ask again for more information.