Is There Any Chance Of Miscarriage Inspite Of Having MTHFR?

Posted on Sat, 15 Mar 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 15 Mar 2014 Answered on

Tue, 1 Apr 2014 Last reviewed on

Question : my last period was 12 feb first beta was 10 march was 54 second 11 march 97 third beta 13 march 193 fourth beta 15 march 371 this mean i am 4 weeks 4 days i think my levels low is these normal ? i have one m/c before due to mthfr c677t hetro , my m/c was after heartbeats at 6 1/2 weeks , is that due to mthfr c677t hetro ?! now i am taking baby aspirin , and innohep 4500 iu inj i am afraid i will m/c again ?

Answered by Dr. Richa Agarwal (3 hours later)

Brief Answer: You should not be afraid but you need evaluation. Detailed Answer: Hi, Thanks for writing to us. Congratulation! As you are suffering from a disease known as a MTHFR c677t heterozygous, the chances of miscarriage are there. In my opinion, you should not be worry and carry your pregnany with some precautions. Here are some suggestions for you- 1) Test your homocystein level. 2) Husband mthfr test whether he is suffering from it or not.(mthfr mutations test) 3) Mother mthfr mutations test. 4) You should be tested for MMA , S-adenocylhomocysteine level. 5) Take appropriate action to ensure safer pregnancy. 6) Continue your pregnancy under supervision of an expert gynaecologist. 7) You should go for your routine blood test and ultrasonography test. Yes, your levels are low but it may improved with hcg injection. So please do not worry. I think I have answered your query If you have further question I will be happy to help you. Good luck. Wish you a happy and safe motherhood. Regards Dr.Richa

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Richa Agarwal (4 minutes later)

thanks alot my homocystine is low 5 regarding my hcg level , its doubling ? so i thought this good

Answered by Dr. Richa Agarwal (28 minutes later)

Brief Answer: Yes, it is very good. Detailed Answer: Hi, Nice to see you again. Yes, It is good that your homocysteine level is normal. Your hcg level is getting double, so it is good for your baby. Now go and get your routine ultrasonography test done, to see foetal sac and yolk sac. I think I have answered your query If you have further question I will be happy to answer you, otherwise rate the answer and close the query. Good luck. Regards Dr. Richa

Above answer was peer-reviewed by : Dr. Raju A.T