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Suggest Treatment For Pelvic Pain And Thickened Endometrium

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Posted on Fri, 30 Jan 2015
Question: Hi, I'm a 48 year old female, had my first child at 22yrs, second child at 32 yrs and my third at 43yrs. I've never had issues getting pregnant. I've always had painful periods. I've always had debilitating breast pain. I'm having a few symptoms of perimenopause, ie hot flashes. My periods have always been heavy for the first few days, then normal to nothing, they usually last for 5 days, my cycles are usually between 23 and 26 days. However, since October they have been irregular, one whole period in October lasted ten days, there was no red blood just different shades of light to dark brown. Ten days later I had heavy bleeding for 2 days, nothing at all for the following 2 days then flooding for 6 days, after this I had a week of nothing, during this week of no bleeding I developed extreme breast pain, this normally arrives after ovulation and not post bleeding, then 2 weeks of severe bleeding, I used 32 tampons and 4 large packets of night time pads. At day 10 in this cycle, I was given A clotting medicine, Tranamexic Acod (spelling). This only served to make the excess bleeding clot, and I then started to pass very large blood clots so e the size of a tennis ball. My haemoglobin was measured as 103. I was admitted to hospital and a scan was done, along with a D&C, Hysteroscopy and biopsy. The scan results showed, a bulky uterus, thickened endometrium measuring 2.7cm ) without internal vascularity, with hectogenous echo texture, suspicious for endrometial hyperplasia and neiplastic lesion needs to be ruled out. No focal lesion within the myomentrium. The right ovary is enlarged measuring 15.ccm with a 2.4x 2.2x 2cm cyst. No evidence of free fluid in pouch of XXXXXXX Since the D&C, the bleeding has stopped and is just very light brown, I still have pelvic pain. I am to have a 4d scan of the ovary in a few weeks and follow up with a gynae to discuss results and treatment. There is cancer of the uterus mad breast in three second degree family members all on my mother's side. Could the ovary be suspicious for a GCT tumor?
doctor
Answered by Dr. Richa Agarwal (47 minutes later)
Brief Answer:
Need more information, GCT is very rare form of ovarian cancer.

Detailed Answer:
Hi,

Thanks for writing to us about it.

I can understand your concern here.

I have gone through your history and with your scan report two things are clear one your uterus is bulky and endometrium thickness is increased and your right side ovary is significantly enlarged in diameter.

There is suspicions of endometrial cancer or ovarian cancer in your case but it needs further testing.

As GCT is very rare form of malignant ovarian cancer and it is not inherited in families the chances of GCT are less.( it needs further testing like MRI and ovarian marker).Benign form of ovarian cancer are more common.

As you mentioned in your history that hysteroscopy and biopsy was done, may I know the report of both.

Please revert back to me with your reports so I will be able to give my opinion better.

Hoping to hear from you soon.

Good luck.
Regards
Dr.Richa









Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Richa Agarwal (1 hour later)
Thank you. I won't know my results until I have a follow up with my gynaecologist, once known, I will provide you with the detail. I was concerned about gct as from what I can understand, it can be caused by too much eostrogen, ie the gct cells produce the eostrogen, which could have caused the endrometrial hyperplasia, sore breasts and a small polyp that was removed during the D&C. Note I haven't taken hormonal contraception since my mid 20's, so where is the excess eostrogen coming from?
doctor
Answered by Dr. Richa Agarwal (8 hours later)
Brief Answer:
Estrogen increased during peri menopause stage, in obesity and PCOD.

Detailed Answer:
Hi,

Nice to hear from you once again.

Sorry for delayed in my response.

I appreciate your knowledge.

It is true that germ cell tumour produce excess of estrogen, maybe it is a cause of your symptoms but it is very rare type of tumour.

There are three other possible cause of excess of estrogen in your case-

- In peri menopausal stage there is excess of estrogen in your body and decreased progesterone level, it may also cause these symptoms.
-If obesity is there it is also one of the cause of excess of estrogen.
-PCOD in which anovulatory cycle cause increased estrogen and decreased progesterone.

Hope it is useful, feel free to ask more.

Good luck.
Regards
Dr.Richa

Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
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Follow up: Dr. Richa Agarwal (39 hours later)
Hi there again,

Thank you for your reply.

There is no history of obesity, I've always been slim, current weight is 124llb (56.4kilos), I'm 5ft 4".

No mention of PCOS, I don't appear to fit the criteria, ie facial hair etc.

I get my results on Thursday from the biopsy, I will provide more detail then.

Thanks
Tracy
doctor
Answered by Dr. Richa Agarwal (8 hours later)
Brief Answer:
Then it can be due to perimenopause.

Detailed Answer:
Hi XXXXXXX

You are most welcome here.

If PCOD and obesity are not the cause then it can be due to perimenopause.

No issues we will await for your reports to confirm the diagnoses.

Hope to hearing from you soon.

Good luck.
Regards
Dr.Richa
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
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Answered by
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Dr. Richa Agarwal

OB & GYN Specialist

Practicing since :1999

Answered : 4031 Questions

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Suggest Treatment For Pelvic Pain And Thickened Endometrium

Brief Answer: Need more information, GCT is very rare form of ovarian cancer. Detailed Answer: Hi, Thanks for writing to us about it. I can understand your concern here. I have gone through your history and with your scan report two things are clear one your uterus is bulky and endometrium thickness is increased and your right side ovary is significantly enlarged in diameter. There is suspicions of endometrial cancer or ovarian cancer in your case but it needs further testing. As GCT is very rare form of malignant ovarian cancer and it is not inherited in families the chances of GCT are less.( it needs further testing like MRI and ovarian marker).Benign form of ovarian cancer are more common. As you mentioned in your history that hysteroscopy and biopsy was done, may I know the report of both. Please revert back to me with your reports so I will be able to give my opinion better. Hoping to hear from you soon. Good luck. Regards Dr.Richa