Brief Answer: See below! Detailed Answer: Hi and thank you so much for trusting us with your health query. 1.Tacrolimus is a drug that is used to suppress the immune system. It is mostly used in patients who have transplant so as to suppress the immune system from rejecting the graft. This same immune system is involved in certain types of skin diseases like eczema which is mediated through the immune system as well. By using this same drug on the surface, we are able to suppress the immune system mediated process leading to this eczema. This means, yes tacrolimus can be prescribed for conditions other than in transplant patients like I just described above. I will not recommend that you stop taking this medication just now. Talk to your doctor and you would certainly find reasons as to why he made the choice. 2. Itches after hot showers need to be evaluated. The most common cause of this could be polycythemia. You would need to talk to your doctor who would do a more detailed questioning, examination and testing to identify the exact cause of this. At times, there is just no real cause identified and measures to relief you of the discomfort are used. 3. Because you are using this drug as a topical agent, it will be very unlikely for you to have a suppressed immune system that can justify infections which are the most common causes of shivering. report this to your doctor for evaluation In all, this drug can be used by persons who did not undergo a transplant. I will recommend that you continue to take it for now but, book an appointment to meet and talk with your doctor about the shivering and the itches after hot baths. I hope you find this helpful. I wish you well. feel free to ask for clarifications and further information if need be. Thanks. Dr. Ditah, MD.

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