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What Does My HIV Test Report Indicate?

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Posted on Mon, 5 Sep 2016
Twitter Mon, 5 Sep 2016 Answered on
Twitter Tue, 27 Sep 2016 Last reviewed on
Question : I went in to get a HIV test because I am pregnant and my first one said " undetermined " the second one was " HIV-1 RNA count, SerPlas, QN, probe -- <48 copy/mL " explain please! does this mean i have it ?
doctor
Answered by Dr. Sameer Kumar (19 minutes later)
Brief Answer:
possibly infected.

Detailed Answer:
Hello,
Thanks for the query to HCM,
An "Undetected" result indicates that the assay was unable to detect HIV-1 RNA in the plasma specimen tested.

A result of "<20 copies/mL" indicates that HIV-1 RNA is detected, but the level present is less than the lower quantification limit of this assay. Due to the increased sensitivity of this assay, patients with previously low or undetectable HIV-1 viral load may show increased or detectable viral load with this assay. However, the clinical implications of a viral load <20 copies/mL remain unclear. Possible causes of such a result include very low plasma HIV-1 viral load present (eg, in the range of 1-19 copies/mL), very early HIV-1 infection (ie, less than 3 weeks from time of infection), or absence of HIV-1 infection (ie, false-positive).
Copies more than 20 i.e less than 48 in your case indicate that you may have suffered an early infection. This can be further confirmed by a NAAT or nucleic acid amplification test or 4th XXXXXXX DUO test.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sameer Kumar (6 minutes later)
is there still a chance i can be in the clear ? or an early infection is present ?
doctor
Answered by Dr. Sameer Kumar (5 minutes later)
Brief Answer:
answered

Detailed Answer:
Hello,

This indicates and early infection and hence i suggested NAAT and 4th gen DUO test, because if they are positive then you are infected and would have to be started on Antiretroviral asap for next 3 months.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sameer Kumar (9 minutes later)
what if the NAAT and 4th gen DUO test come out negative ?
doctor
Answered by Dr. Sameer Kumar (1 minute later)
Brief Answer:
answered

Detailed Answer:
Hello,
In that case you are not infected. But it is unlikely because HIV 1 RNA serials is also a very sensitive test. I am requesting a double confirmation at your end before antivirals can be started.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Sameer Kumar

OB and GYN Specialist

Practicing since :2002

Answered : 1776 Questions

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What Does My HIV Test Report Indicate?

Brief Answer: possibly infected. Detailed Answer: Hello, Thanks for the query to HCM, An "Undetected" result indicates that the assay was unable to detect HIV-1 RNA in the plasma specimen tested. A result of "<20 copies/mL" indicates that HIV-1 RNA is detected, but the level present is less than the lower quantification limit of this assay. Due to the increased sensitivity of this assay, patients with previously low or undetectable HIV-1 viral load may show increased or detectable viral load with this assay. However, the clinical implications of a viral load <20 copies/mL remain unclear. Possible causes of such a result include very low plasma HIV-1 viral load present (eg, in the range of 1-19 copies/mL), very early HIV-1 infection (ie, less than 3 weeks from time of infection), or absence of HIV-1 infection (ie, false-positive). Copies more than 20 i.e less than 48 in your case indicate that you may have suffered an early infection. This can be further confirmed by a NAAT or nucleic acid amplification test or 4th XXXXXXX DUO test. Regards