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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can SAMe Be Taken Along With 5-HTP? How Beneficial Is It And What Is The Dosage?

I have just weened myself off of Zoloft; I talked to my doctor first, and told him I wanted to try natural supplements. I have bought some 5-htp, which I ve read is beneficial for depression along with anxiety-that is what I have. Can I also take SAMe with the 5-htp, not necessarily at the same time. I thought that taking the 5-htp at bedtime might be best, because I read that it helps with sleep problems also. The SAMe is said to help with arthritis and joint pain along with the mood lifting and is most beneficial for seniors. So, do you think that sounds ok, and at what dosages. Thank you for your help.
posted on Tue, 10 Dec 2013
Twitter Wed, 11 Dec 2013 Answered on
Twitter Wed, 11 Dec 2013 Last reviewed on
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General & Family Physician,  's  Response
HELLO ,WELCOME TO HCM.

YOU WERE INTIALLY TAKING SERTRALINE(ZOLOFT) FOR DEPRESSION BUT NOW YOU ARE ON 5 HTP AND SAMe.

SAMe S ADENOSYL methionine has a beneficial effect on depression by enhancing the production of serotonin.

5 HTP ALSO HAS SIMILAR PROPERTIES BUT THERE HAVE BEEN REPORTS OF SEVERE MUSCLE PAIN INSOME PERSONS TAKING THE MEDICATION.

SAMe on the other hand has no severe side effects reported so far.
you can take 200 mg thrice daily.

ALWAYS CONSULT YOUR PHYSICIAN IF YOUR SYMPTOMS DO NOT IMPROVE OR WORSEN..
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Can SAMe Be Taken Along With 5-HTP? How Beneficial Is It And What Is The Dosage?

HELLO ,WELCOME TO HCM. YOU WERE INTIALLY TAKING SERTRALINE(ZOLOFT) FOR DEPRESSION BUT NOW YOU ARE ON 5 HTP AND SAMe. SAMe S ADENOSYL methionine has a beneficial effect on depression by enhancing the production of serotonin. 5 HTP ALSO HAS SIMILAR PROPERTIES BUT THERE HAVE BEEN REPORTS OF SEVERE MUSCLE PAIN INSOME PERSONS TAKING THE MEDICATION. SAMe on the other hand has no severe side effects reported so far. you can take 200 mg thrice daily. ALWAYS CONSULT YOUR PHYSICIAN IF YOUR SYMPTOMS DO NOT IMPROVE OR WORSEN..