Can an allergic/Immunologic reaction to Orthopedic Implant made of an Iron Alloy (Surgical Stainless Steel) and Polyethylene Suture cause severe neurologic and CNS disturbance ? Can elevated Ferritin level of 677.9 in adult male be caused by the Iron Alloy? Is removal of the Implant the best course of action and how can we locate an OS who is willing to remove the implant? Hx: The patient is 53 year old male, who sustained an on the job injury to his left shoulder. Prior to the injury he was a healthy, robust individual, w/o physical ailment. He never smoked, drank alcohol, or engaged in drug use. Exercised regularly and participated in Martial Arts. He underwent a left shoulder arthroscopy (July 2012) for repair of partial rotator cuff tear. Within one month of the surgery his health begin to deteriorate. He is now unable to engage in ADL(bathing, dressing, and feeding) he is bed bound (except for trips to the various doctors), ambulates with a walker (ataxic gait) and assistance from family members, weight loss of more than 40 lbs. and severe headaches. His memory, speech, vision and coordination have been affected and he is now insulin dependent. He has undergone extensive medical testing. Nuerological dx: Encephalitis Cerebellitis with a finding of voltage gated potassium channel autoimmunity. Testing for autoimmune deseases and a variety of cancers have come back negative. Four rounds of IG intravenous treatments were given, but there was no improvement in his condition. Since his symptoms begin shortly after the shoulder surgery, his family begin to suspect a connection. Through research we found medical assistace and tested for heavy metals and other possible allergens. Results showed: Antimony, Lead, at elavated levels (above reference range), aluminum and nickel were also present, within ref. range, Gadolinium was extremely high (believed to be due to numerous contrasting MRIs that he has recieved) and Ferritin at nearly 3x the level that it should be. We know for sure that the implant and suture each consist of some combination of these metals. Chelation therapy was started (the end of Nov 2013), after the second treatment he begin to show some small signs of improvement. Now, headaches have stopped, coordination has improved- still ambulates with a walker, but he is steadier on his feet, he can shower and shave and feed himself again. We are cautiously optimistic that a nearly full recover maybe possible, if we can remove the source and continue to clean his system. We have asked the orthopaedic surgeon who performed the surgery about removal of the implant, but he maintains that such a reaction is not possible and he is refusing to remove. Besides the patient has lost confidence in this surgeon and has indicated that he wants another OS. Thank you for any help and advice that you can provide.