Hallow Dear,
Polycystic Ovarian Syndrome (PCOS) is a multi-systemic complex disorder. There are dysfunction of reproductory system (delayed menses and no egg formation), metabolic system (high insulin levels) and
hormonal dysfunction (high male hormones) in PCOS. While treating for
infertility, all these three systems have to be addressed.
Because the follicles do not rupture and release eggs, the ovaries form multiple cysts; hence Polycystic Ovarian Syndrome.
For egg release (induction of ovulation), some medicines are required.
Clomiphene citrate is given initially. Along with it,
Metformin is also given which helps control the raised insulin. Now a days, instead of Metformin, Myo-Inocitol is being tried which along with insulin levels brings down the male hormones levels also. Myo Inocitol is claimed to give better results as far as the conception is concerned.
Clomiphene citrate should not be tried for more than 6 months. If it fails, then HMG/hCG combination is given to induce the ovulation. If both these do not offer success, Laparoscopic drilling of the ovaries also may be tried.
Weight gain is another problem in PCOS. To treat PCOS and achieve fertility, weight reduction programme is very essential. BMI should be maintained between 18 and 24.9. For weight reduction, high protein and low
carbohydrate low fat diet along with exercises is advised. Please calculate your BMI based on your height and weight and then take the action accordingly.
You had previous two unsuccessful pregnancies. So, it seems that you have developed PCOS after the last
pregnancy. Stress also is one of the precipitating factor for PCOS.
I hope this helps you planning your further management of infertility due to PCOS.
Dr. Nishikant Shrotri