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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Lyrica Be Combined With Amtripaline?

I am a male 40 years of age, I am on Lyrica. My doctor prescribed Amtripaline, I took my first pill and shortly after the top front of my head (Hair line area) began to hurt, shortly after I had a headache, so severe it was unbearable. It took roughly 24 hours for this head ache to subside. My question is, are these two combinations of drugs compatable?
posted on Thu, 19 Jun 2014
Twitter Tue, 21 Apr 2015 Answered on
Twitter Tue, 21 Apr 2015 Last reviewed on
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Internal Medicine Specialist,  's  Response
Hello,

These drugs may have a worrisome interaction. They may have additive effect the on central nervous system and respiratory system depression. In many cases this is not a serious concern, but it may become one. Amitriptyline may cause headache -it's a documented side effect. Perhaps you should discuss this symptom with your doctor to search for alternatives.

Besides that, severe headache is a good reason to visit your doctor to exclude serious diagnoses.

Contact me again if you'd like further information.

Kind regards!
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Can Lyrica Be Combined With Amtripaline?

Hello, These drugs may have a worrisome interaction. They may have additive effect the on central nervous system and respiratory system depression. In many cases this is not a serious concern, but it may become one. Amitriptyline may cause headache -it s a documented side effect. Perhaps you should discuss this symptom with your doctor to search for alternatives. Besides that, severe headache is a good reason to visit your doctor to exclude serious diagnoses. Contact me again if you d like further information. Kind regards!