Sign-in to Ask A Doctor - 24x7
OR
Sign in with GoogleGet your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
Can Overdose Of Tylenol Cause Any Harm In Pregnancy ?
I am 16 weeks pregnant and have been getting horrible migraines. My doctor said Tylenol is fine to take, but tonight I took two extra strength Tylenol and then took a second dose three and a half hours later by accident. Should I be worried about overdosing? Altogether I have take six extra strength Tylenols today
posted on
Fri, 14 Mar 2014
Medically reviewed by
Ask A Doctor - 24x7 Medical Review Team
Tue, 5 Nov 2019
Answered on
Wed, 13 Nov 2019
Last reviewed on
Hi,
Yes. Acetaminophen (APAP) is the most common drug overdose in pregnancy. APAP has been demonstrated to cross the placenta and in toxic doses may harm the fetal and maternal hepatocytes. Fetal hepatocytes metabolize APAP into both active and toxic metabolites. These toxic metabolites may cause fetal hepatic necrosis.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Ajeet Singh, General & Family Physician
Yes. Acetaminophen (APAP) is the most common drug overdose in pregnancy. APAP has been demonstrated to cross the placenta and in toxic doses may harm the fetal and maternal hepatocytes. Fetal hepatocytes metabolize APAP into both active and toxic metabolites. These toxic metabolites may cause fetal hepatic necrosis.
Hope I have answered your query. Let me know if I can assist you further.
Regards,
Dr. Ajeet Singh, General & Family Physician
I find this answer helpful
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer.
For a more detailed, immediate answer, try our premium service
[Sample answer]
Related questions you may be interested in
Recent questions on Tylenol
Loading Online Doctors....