Hi, Inflammation of the head of the penis or glans penis is known as balanitis. Whitish thin layer around the head of penis may be a clinical feature of balanitis. It may resulted from fungal or bacterial infections, STIs or sexually transmitted diseases like gonorrhea, trichomoniasis etc., exposure to irritants or allergic reactions, scabies, diabetes mellitus, reactive arthritis and many more. It also may resulted from some drugs induced allergic reactions such as some antibiotics like penicillin and some painkillers like ibuprofen. Advil contains ibuprofen that acts as a painkiller. So, balanitis can be resulted from both penicillin and ibuprofen. As you had history of developing balanitis or same symptoms during taking ibuprofen or penicillin, so both penicillin and ibuprofen may be responsible for causing balanitis. You should stop both ibuprofen and penicillin immediately due to their allergic reactions and inform your doctor first. Your doctor may prescribe another antibiotics and painkiller for you. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician