Okay - thank you. I am a 63 yr old woman and have never had any problems with bleeding from my rectum. Over the last few months I contracted Pertussis and it went undiagnosed for weeks. I took Doxacycline, inhalers, cough medicine with Codine, steroids, more inhalers, finally a Zpack that got rid of the pertussis. I feel pretty weak still. About two weeks after I had finished the Zpack and then took the Tdap immunization shot my husband and I went on a trip that involved a lot of time in an airplane. The day after we arrived I developed edema (something I have never had) and i ended up taking water pills with caffeine - probably about 10 or 12 of them before I got better. Now we are home since Turesday night and on Thursday night I passed a large amount of blood (maybe a 1/4 cup) when I went to the bathroom. Something that has never happened. Do you think that the stress of my trip and the edema and water pills could be a cause of this bleeding??? I have scheduled a colonoscopy for next Tuesday.