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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Substituting Oxycodone With Hydrocodone Cause Rashes And Blisters?

my dr changed my script from oxycodone to hydrocodone and I have developed quite a heavy rash. I thought it might be [poison ivy but noticed that im the only one in the family with the rash , seeping blisters. is it a possible reaction to the med switch ?
Fri, 30 Nov 2018
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General Surgeon 's  Response
Hello,

Hydrocodone can sometimes cause an allergic reaction to susceptible individuals.

As a first line management, you can take antihistamines like pheniramine for symptomatic relief. It is better to switch back to oxycodone.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Shinas Hussain, General & Family Physician
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Can Substituting Oxycodone With Hydrocodone Cause Rashes And Blisters?

Hello, Hydrocodone can sometimes cause an allergic reaction to susceptible individuals. As a first line management, you can take antihistamines like pheniramine for symptomatic relief. It is better to switch back to oxycodone. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Shinas Hussain, General & Family Physician