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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Do Sulfides And Disulfides Have The Same Effects?

I am allergic to sulfa drugs, which nauseate me to the point of vomiting.Tetramethylthiuram disulfide, present in rubber products, may show cross-sensitivity to disulfiram (the active ingredient contained in Antabuse). Are sulfides and disulfides that same thing?YYYY@YYYY is my email and name. Thank you for the information
Mon, 18 May 2015
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General & Family Physician,  's  Response
Hi
Thanks for posting your query.

Sulfonamides ( like antibiotics, water pills, anti diabetic drugs, some pain killers) are known to cause allergic reactions because of the sulfur content in their chemical structures.
On the other hand even though Disulfiram (Antabuse) which is used as "aversion therapy" in Alcohol de-addiction has a sulfur in its structure is different from Sulfonmides and hence not known to cause such allergic reaction.

Sulfonamides and Disufiram are two differently related compounds.
Further, there is no cross allergenicity between Disulfiram and Sulfonmides.

Hope this answers your query.
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Do Sulfides And Disulfides Have The Same Effects?

Hi Thanks for posting your query. Sulfonamides ( like antibiotics, water pills, anti diabetic drugs, some pain killers) are known to cause allergic reactions because of the sulfur content in their chemical structures. On the other hand even though Disulfiram (Antabuse) which is used as aversion therapy in Alcohol de-addiction has a sulfur in its structure is different from Sulfonmides and hence not known to cause such allergic reaction. Sulfonamides and Disufiram are two differently related compounds. Further, there is no cross allergenicity between Disulfiram and Sulfonmides. Hope this answers your query.