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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Imipramine Interact With Cymbalta And Amlodipine?

I am taking the following medications:Cymbalta, Amlodipin Bestylate,Imipramine,and Pravastatin Sodium. Have taken all of them for years...Recently I started taking Plexus Products which have Chromium as the main ingredient. I have had headaches, anxiety and mood swings..crying... Is the Chromium interacting with what I take?
Tue, 20 Feb 2018
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General & Family Physician,  's  Response
Hi & Welcome.

Yes, Imipramine may interact with Cymbalta.

Commonly prescribed in the treatment of depression and nocturnal enuresis (night time bed wetting) Imipramine may interact with Cymbalta and increase the risk of a rare but serious condition called the "serotonin syndrome" causing confusion, hallucination, seizure, increased blood pressure and heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremor, stomach cramp, vomiting, and diarrhea.

Chromium found in the Plexus Products is not known to cause any harmful interactions with the medications listed in your query.

Hope I could answer your query.

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Does Imipramine Interact With Cymbalta And Amlodipine?

Hi & Welcome. Yes, Imipramine may interact with Cymbalta. Commonly prescribed in the treatment of depression and nocturnal enuresis (night time bed wetting) Imipramine may interact with Cymbalta and increase the risk of a rare but serious condition called the serotonin syndrome causing confusion, hallucination, seizure, increased blood pressure and heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremor, stomach cramp, vomiting, and diarrhea. Chromium found in the Plexus Products is not known to cause any harmful interactions with the medications listed in your query. Hope I could answer your query.