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Does Tylenol Affect One’s Kidneys?
i am looking for a doctor that can give me meds i have been to 5 neurosurgens they cannot do surgery because i am allergic to all metal including titanium, i also have severe arthritis in both knees this happened in 2000. i was on stronger meds now i am on tylenol3 thought it was affecting my kidneys went to a urilogy they said it was caused from my back but tylonel 3 but said with taking tylenol can affect it if taken for a lond period of time
Sat, 10 Feb 2018
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Dear approximately 1-2% of patients with acetaminophen overdose. The pathophysiology of renal toxicity in acetaminophen poisoning has been attributed to cytochrome P-450 mixed function oxidase isoenzymes present in the kidney, although other mechanisms have been elucidated, including the role of prostaglandin synthetase and N-deacetylase enzymes. Paradoxically, glutathione is considered an important element in the detoxification of acetaminophen and its metabolites; however, its conjugates have been implicated in the formation of nephrotoxic compounds. Acetaminophen-induced renal failure becomes evident after hepatotoxicity in most cases.
But n acetylene cysteine may be not udeful in nephrotoxicity.
I think I answered to your question if you have more questions feel free to ask.
Take care dear
Thank you for trusting HCM
Dear approximately 1-2% of patients with acetaminophen overdose. The pathophysiology of renal toxicity in acetaminophen poisoning has been attributed to cytochrome P-450 mixed function oxidase isoenzymes present in the kidney, although other mechanisms have been elucidated, including the role of prostaglandin synthetase and N-deacetylase enzymes. Paradoxically, glutathione is considered an important element in the detoxification of acetaminophen and its metabolites; however, its conjugates have been implicated in the formation of nephrotoxic compounds. Acetaminophen-induced renal failure becomes evident after hepatotoxicity in most cases.
But n acetylene cysteine may be not udeful in nephrotoxicity.
I think I answered to your question if you have more questions feel free to ask.
Take care dear
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