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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Vicoodin Cause Elevated ALT And AST Levels?

Over the summer I had a blood test done because I was going to get Lamisil for a toenail fungus. When the results came back they told me that my AST=48 and ALT=76. I told them I was using Vicodin/Acteamenophin for back pain and they suggested I go off the vicodin and re-take then blood test and I never did. Last week I went to my PCP for my annual check up and he informed me that my AST=52 and ALT=145. I still had been using the Vicoodin for up until last week. Could the vicodin actually cause my resuts to be this high? I have to go back in a month for a retest, I am completely going to stop any vicodin, advil and will not drink any alcohol.
Fri, 14 Aug 2020
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Internal Medicine Specialist,  's  Response
Hello,

Vicodin is a combination of hydrocodone and acetaminophen. Acetaminophen can produce liver injury which is often dose related. If you stop Vicodin and other medicines containing acetaminophen and if the retest shows a decrease in AST and ALT, then the elevation was likely to be related to Vicodin. If these persist, then other causes have to be searched for.


Take care. Hope I have answered your question. Let me know if I can assist you further.



Regards,

Dr. Noble Zachariah, Internal Medicine Specialist
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Does Vicoodin Cause Elevated ALT And AST Levels?

Hello, Vicodin is a combination of hydrocodone and acetaminophen. Acetaminophen can produce liver injury which is often dose related. If you stop Vicodin and other medicines containing acetaminophen and if the retest shows a decrease in AST and ALT, then the elevation was likely to be related to Vicodin. If these persist, then other causes have to be searched for. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Noble Zachariah, Internal Medicine Specialist