Hello Nitin, Decdan (pharmacologically Dexamethasone) is a cortico steroid & Practin (pharmacologically Cyproheptadine, is an antihistamine). Long term side effects of these medications include high blood pressure, electrolyte imbalance, headache, muscle weakness, puffiness of face, thinning and easy bruising of skin, glaucoma, cataracts, peptic ulceration, worsening of diabetes, mood swings, personality changes, etc. So, before choosing any such tablet or health supplement, it is advisable to consult your family physician once. Moreover, you should not compromise on routine healthy food such as: 1. Consume more of natural diet like fresh fruits, green vegetables, milk, eggs, wheat, etc. 2. Avoid oily and junk food. 3. Stay away from smoking & alcohol. Despite these measures, if you experience difficulty, it will be better to rule other causes of underweight. Investigations like complete blood count, thyroid profile, estimation of blood sugar level will be helpful to rule out any chronic infection, hormonal and metabolic causes. Wishing you a healthy life. Take care.